The most common conditions

Title Effect Research Type Journal Year
Microarray and pathway analysis reveal distinct mechanisms underlying cannabinoid-mediated modulation of LPS-induced activation of BV-2 microglial cells. positive cells PloS one 2013
Anti-inflammatory role of cannabidiol and O-1602 in cerulein-induced acute pancreatitis in mice. positive animals Pancreas 2013
Topical and systemic cannabidiol improves trinitrobenzene sulfonic acid colitis in mice. positive animals Pharmacology 2012
Cannabidiol affects the expression of genes involved in zinc homeostasis in BV-2 microglial cells. positive cells Neurochemistry international 2012
Cannabinoids mediate opposing effects on inflammation-induced intestinal permeability. positive cells British journal of pharmacology 2012
Differential transcriptional profiles mediated by exposure to the cannabinoids cannabidiol and Δ9-tetrahydrocannabinol in BV-2 microglial cells. positive cells British journal of pharmacology 2012
Role of myeloid-derived suppressor cells in amelioration of experimental autoimmune hepatitis following activation of TRPV1 receptors by cannabidiol. positive animals PloS one 2011
Cannabidiol reduces lipopolysaccharide-induced vascular changes and inflammation in the mouse brain: an intravital microscopy study. positive animals Journal of neuroinflammation 2011
Pharmacological effects of cannabinoids on the Caco-2 cell culture model of intestinal permeability. positive cells The Journal of pharmacology and experimental therapeutics 2010
The effects of Delta-tetrahydrocannabinol and cannabidiol alone and in combination on damage, inflammation and in vitro motility disturbances in rat colitis. positive animals British journal of pharmacology 2010
Cannabinoids Delta(9)-tetrahydrocannabinol and cannabidiol differentially inhibit the lipopolysaccharide-activated NF-kappaB and interferon-beta/STAT proinflammatory pathways in BV-2 microglial cells. positive cells The Journal of biological chemistry 2010
Oral administration of cannabis with lipids leads to high levels of cannabinoids in the intestinal lymphatic system and prominent immunomodulation. positive animals Scientific reports 2017
Cannabidiol and palmitoylethanolamide are anti-inflammatory in the acutely inflamed human colon. positive cells Clinical science (London, England : 1979) 2017
Cannabidiol and palmitoylethanolamide are anti-inflammatory in the acutely inflamed human colon. positive cells Clinical science (London, England : 1979) 2017
Neuroprotective effects of cannabidiol in endotoxin-induced uveitis: critical role of p38 MAPK activation. positive cells Molecular vision 2008
Mediation of cannabidiol anti-inflammation in the retina by equilibrative nucleoside transporter and A2A adenosine receptor. positive cells Investigative ophthalmology & visual science 2008
Low-Dose Cannabidiol Is Safe but Not Effective in the Treatment for Crohn's Disease, a Randomized Controlled Trial. NONE humans Digestive diseases and sciences 2017
Low-Dose Cannabidiol Is Safe but Not Effective in the Treatment for Crohn's Disease, a Randomized Controlled Trial. NONE humans Digestive diseases and sciences 2017
Cannabidiol, unlike synthetic cannabinoids, triggers activation of RBL-2H3 mast cells. positive cells Journal of leukocyte biology 2007
Experimental cannabidiol treatment reduces early pancreatic inflammation in type 1 diabetes. positive animals Clinical hemorheology and microcirculation 2016
An Orally Active Cannabis Extract with High Content in Cannabidiol attenuates Chemically-induced Intestinal Inflammation and Hypermotility in the Mouse. positive animals Frontiers in pharmacology 2016
Inhibition of an equilibrative nucleoside transporter by cannabidiol: a mechanism of cannabinoid immunosuppression. positive animals Proceedings of the National Academy of Sciences of the United States of America 2006
Cannabidiol inhibits inducible nitric oxide synthase protein expression and nitric oxide production in beta-amyloid stimulated PC12 neurons through p38 MAP kinase and NF-kappaB involvement. positive cells Neuroscience letters 2006
Neuroprotective and blood-retinal barrier-preserving effects of cannabidiol in experimental diabetes. positive animals The American journal of pathology 2006
Abnormal cannabidiol attenuates experimental colitis in mice, promotes wound healing and inhibits neutrophil recruitment. positive animals Journal of inflammation (London, England) 2016
Pathways and gene networks mediating the regulatory effects of cannabidiol, a nonpsychoactive cannabinoid, in autoimmune T cells. positive cells Journal of neuroinflammation 2016
Anti-inflammatory effects of the cannabidiol derivative dimethylheptyl-cannabidiol - studies in BV-2 microglia and encephalitogenic T cells. positive cells Journal of basic and clinical physiology and pharmacology 2016
The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis. positive animals Proceedings of the National Academy of Sciences of the United States of America 2000
Cannabidiol, a non-psychoactive cannabinoid, leads to EGR2-dependent anergy in activated encephalitogenic T cells. positive cells Journal of neuroinflammation 2015
Cannabidiol improves lung function and inflammation in mice submitted to LPS-induced acute lung injury. positive animals Immunopharmacology and immunotoxicology 2015
Cannabidiol provides long-lasting protection against the deleterious effects of inflammation in a viral model of multiple sclerosis: a role for A2A receptors. positive cells Neurobiology of disease 2013
Title Effect Research Type Journal Year
Cannabis induces a clinical response in patients with Crohn's disease: a prospective placebo-controlled study. positive humans Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2013
Microarray and pathway analysis reveal distinct mechanisms underlying cannabinoid-mediated modulation of LPS-induced activation of BV-2 microglial cells. positive cells PloS one 2013
Cannabinoids mediate opposing effects on inflammation-induced intestinal permeability. positive cells British journal of pharmacology 2012
Pharmacological effects of cannabinoids on the Caco-2 cell culture model of intestinal permeability. positive cells The Journal of pharmacology and experimental therapeutics 2010
The effects of Delta-tetrahydrocannabinol and cannabidiol alone and in combination on damage, inflammation and in vitro motility disturbances in rat colitis. positive animals British journal of pharmacology 2010
Cannabinoids Delta(9)-tetrahydrocannabinol and cannabidiol differentially inhibit the lipopolysaccharide-activated NF-kappaB and interferon-beta/STAT proinflammatory pathways in BV-2 microglial cells. positive cells The Journal of biological chemistry 2010
Oral administration of cannabis with lipids leads to high levels of cannabinoids in the intestinal lymphatic system and prominent immunomodulation. positive animals Scientific reports 2017
Attenuation of experimental autoimmune hepatitis by exogenous and endogenous cannabinoids: involvement of regulatory T cells. positive animals Molecular pharmacology 2008
Δ9-Tetrahydrocannabinol reverses TNFα-induced increase in airway epithelial cell permeability through CB2 receptors. positive cells Biochemical pharmacology 2016
Anti-inflammatory and antioxidant effects of a combination of cannabidiol and moringin in LPS-stimulated macrophages. positive cells Fitoterapia 2016
Activation through cannabinoid receptors 1 and 2 on dendritic cells triggers NF-kappaB-dependent apoptosis: novel role for endogenous and exogenous cannabinoids in immunoregulation. positive animals Journal of immunology (Baltimore, Md. : 1950) 2004
Marijuana-derived Δ-9-tetrahydrocannabinol suppresses Th1/Th17 cell-mediated delayed-type hypersensitivity through microRNA regulation. positive animals Journal of molecular medicine (Berlin, Germany) 2016
Cannabinoid receptor CB2 is involved in tetrahydrocannabinol-induced anti-inflammation against lipopolysaccharide in MG-63 cells. positive cells Mediators of inflammation 2015
Δ(9) Tetrahydrocannabinol attenuates Staphylococcal enterotoxin B-induced inflammatory lung injury and prevents mortality in mice by modulation of miR-17-92 cluster and induction of T-regulatory cells. positive animals British journal of pharmacology 2015
Chronic administration of Δ9-tetrahydrocannabinol induces intestinal anti-inflammatory microRNA expression during acute simian immunodeficiency virus infection of rhesus macaques. positive animals Journal of virology 2015
Ultralow doses of cannabinoid drugs protect the mouse brain from inflammation-induced cognitive damage. positive animals Journal of neuroscience research 2014
Cannabinoid inhibits HIV-1 Tat-stimulated adhesion of human monocyte-like cells to extracellular matrix proteins. positive cells Life sciences 2014
Title Effect Research Type Journal Year
Pro-resolution, protective and anti-nociceptive effects of a cannabis extract in the rat gastrointestinal tract. positive animals Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2013